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    first people were horrified that a poison would be used to take away their wrinkles. What were the risks? What needs to be clarified is that you’re injecting a product of the botulism bacterium in the same way that penicillin is a product of a mold. Most antibi
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    The discovery of Botox: the wonder product that turns back the clock - happened by accident.

    In the 1820s, a German doctor, Justinus Kerner began experimenting with Botulinum toxin; a toxic protein produced by the bacterium, Clostridium botulinum, which causes botulism (a deadly form of food poisoning, that thrives in home-canned food and has caused many deaths through the centuries).

    But Kerner wanted to make use of the bacterium’s muscle-weakening qualities for therapeutic use. His work laid the foundation for the discovery that the toxin could be used to relieve muscle spasms –specifically, by blocking the release of acetylcholine, a neurotransmitter that tells muscles when to contract.

    Inspired by this discovery, a dermatologist and ophthomologist, Alistair and Jean Carruthers, began injecting patients mainly for muscular disorders of the eye, and the results were successful. When her assistant suggested she inject her pronounced frown area, between the eyebrows, above the nose (referred to as ‘glabellar lines’). A phenomenon was born.

    At first people were horrified that a poison would be used to take away their wrinkles. What were the risks? What needs to be clarified is that you’re injecting a product of the botulism bacterium in the same way that penicillin is a product of a mold. Most antibi
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    ulism (a deadly form of food poisoning, that thrives in home-canned food and has caused many deaths through the centuries).

    But Kerner wanted to make use of the bacterium’s muscle-weakening qualities for therapeutic use. His work laid the foundation for the discovery that the toxin could be used to relieve muscle spasms –specifically, by blocking the release of acetylcholine, a neurotransmitter that tells muscles when to contract.

    Inspired by this discovery, a dermatologist and ophthomologist, Alistair and Jean Carruthers, began injecting patients mainly for muscular disorders of the eye, and the results were successful. When her assistant suggested she inject her pronounced frown area, between the eyebrows, above the nose (referred to as ‘glabellar lines’). A phenomenon was born.

    At first people were horrified that a poison would be used to take away their wrinkles. What were the risks? What needs to be clarified is that you’re injecting a product of the botulism bacterium in the same way that penicillin is a product of a mold. Most antibi
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    very that the toxin could be used to relieve muscle spasms –specifically, by blocking the release of acetylcholine, a neurotransmitter that tells muscles when to contract.

    Inspired by this discovery, a dermatologist and ophthomologist, Alistair and Jean Carruthers, began injecting patients mainly for muscular disorders of the eye, and the results were successful. When her assistant suggested she inject her pronounced frown area, between the eyebrows, above the nose (referred to as ‘glabellar lines’). A phenomenon was born.

    At first people were horrified that a poison would be used to take away their wrinkles. What were the risks? What needs to be clarified is that you’re injecting a product of the botulism bacterium in the same way that penicillin is a product of a mold. Most antibi
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    egan injecting patients mainly for muscular disorders of the eye, and the results were successful. When her assistant suggested she inject her pronounced frown area, between the eyebrows, above the nose (referred to as ‘glabellar lines’). A phenomenon was born.

    At first people were horrified that a poison would be used to take away their wrinkles. What were the risks? What needs to be clarified is that you’re injecting a product of the botulism bacterium in the same way that penicillin is a product of a mold. Most antibi
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    first people were horrified that a poison would be used to take away their wrinkles. What were the risks? What needs to be clarified is that you’re injecting a product of the botulism bacterium in the same way that penicillin is a product of a mold. Most antibiotics are natural products of other micro-organisms, and Botox is no different.

    The Treatment Approved
    In 1989 the U.S. Food and Drug Administration had approved Botox® for treatment of crossed eyes and uncontrollable blinking (Blepharospams) and in 2000 for a neurological movement disorder known as cervical dystonia. In 2002 it was approved for a single cosmetic procedure: reduction of glabellar lines (frown lines).

    Botox® works for three to six months depending on the dosage and physiology. But in tiny quantities, the toxin acts as a muscle-relaxing agent by blocking the release of acetylcholine in the nerve endings. It is administered by units, each equaling precisely the dose it takes to kill a mouse. A typical cosmetic treatment is 20 units per ‘site’.

    Although, treating glabellar lines constitutes the only cosmetic use indicated by the FDA and Allergan, doctors routinely inject other facial areas: crow’s feet around the eyes, laugh lines, and creases near the nose. Once injected, practitioners contend, the toxin ‘spreads’ by no more th

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